Liquefied natural gas (LNG) reserve and peak-shaving projects are key infrastructure for urban energy supply guarantee and pipeline network safety, and they have characteristics such as low temperature, high pressure, flammability and explosiveness, long process chains, and dense cross-operations, making their safety management complexity and risk levels significantly higher than those of conventional engineering. The “one primary, four confirmations, and four participations” safety concept takes the territorial dominance of team leaders as the core, utilizes four-party joint confirmation as the starting point for front-end risk prevention and control, and employs diverse full-staff participation as the on-site supervision guarantee, thereby constructing a full-process closed-loop safety management and control system of “responsibility to post, confirmation to point, and supervision to personnel”. Combining the full-cycle scenarios of LNG liquefaction, storage, gasification, outbound transmission, and maintenance, this paper systematically explained the concept connotation and operation logic and deeply explored the implementation path, practical effectiveness, existing problems, and optimization directions in the construction and operation of LNG reserve and peak-shaving projects from the dimensions of organizational structure, institutional processes, on-site execution, digital and intelligent empowerment, emergency linkage, and performance guarantee. It provides a replicable practice paradigm and theoretical reference for the standardized and refined safety management of similar energy engineering.